Blue Brain Portal

Rat Hippocampus CA1

The multi-compartmental models of adult rat hippocampus neurons were constrained through the use of reconstructed morphologies, recorded electrophysiological traces, and automated parameter optimization (Van Geit et al 2016). The models were subsequently validated for emergent properties as post-synaptic potential attenuation and back-propagating action potential (Migliore et al., 2018, submitted).  These rat models are part of the Blue Brain collaboration with the Human Brain Project consortium. They are available on the Human Brain Project Brain Simulation Platform.